高野 博嘉 教授・勝木 淳 教授・斉藤 寿仁 教授
これまでの研究で、バースト高周波電界によるDNA損傷、水中プラズマ照射による水中生物の形態変化など、パルスパワーによって引き起こされるユニークな生体反応が観察されています。基礎バイオエレクトリクス分野では、このパルスパワー特有の生体現象において、ストレスを受ける因子は何か?どのような反応経路か?またそれは制御可能か?のように、現象の理解と制御を目指して研究を行っています。
Publications
- Fukuda, I., Ito, A., Uramoto, M, Saitoh, H., Kawasaki, H., Osada, H., Yoshida, M. (2008) Kerriamycin B inhibits protein SUMOylation. J. Antibiotics, in press.
- Izumi, Y., Kuroki, J., Nagafuji, H., Lin, X. and Takano, H. (2009) Effects of antibiotics that inhibit bacterial peptidoglycan synthesis on plastid division in pteridophytes. Cytologia, in press
- Nomura, N., Yano, M., Katsuki, S., Akiyama, H., Abe, K., Abe, S-I. (2009) Intracellular DNA Damage Induced by non-thermal, intense narrowband electric fields, IEEE Transactions on Dielectrics and Electrical Insulation, in press.
- Choi, J., Matsuo, K., Yoshida, H., Hosseini, S.H.R., Namihira, T., Katsuki, S., Akiyama, H. (2009) Fluid mechanics of torch appearance in capillary microplasma jet., Japanese Journal of Applied Physics 48 (1), no. 016001
- Fukuda, I., Ito, A., Hirai, G., Nishimura, S., Kawasaki, H., Saitoh, H., Kimura, K., Sodeoka, M., Yoshida, M. (2009) Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate., Chemistry & Biology 16, 133-140.
- Saitoh, H., Uwada, J., Kawasaki, A. (2009) Strategies for the expression of SUMO-modified target proteins in Escherichia coli., Methods in Molecular Biology 497, 211-221.
- Takaki, K., Katsuki, S. (2009) Industrial Applications of Pulsed Power Technology, Electrical Engineering in Japan 129, pp.62-66.
- Choi, J., Wang, D., Namihira, T., Katsuki, S., Akiyama, H., Lin, X., Sato, H., Saeki, T. (2008) Inactivation of spores using pulsed electric field in a pressurized flow system., Journal of Applied Physics 104 (9), no. 094701
- Fudamoto, T., Namihira, T., Katsuki, S., Akiyama, H., Imakubo, T., Majima, T. (2008) Sterilization of E. coli by underwater pulsed streamer discharges in a continuous flow system., Electrical Engineering in Japan 164 (1), pp.1-7
- Garcia, M., Myouga, F., Takechi, K., Sato, H., Nabeshima, K., Nagata, N., Takio, S., Shinozaki, K., Takano, H. (2008) An Arabidopsis homolog of the bacterial peptidoglycan synthesis enzyme MurE has an essential role in chloroplast development. Plant J. 53, 924-934.
- Katsuki, S., Akiyama, H. (2008) Pulsed power driven discharge plasma EUV sources, Japan Society of Applied Physics 77 (4), pp.375-382
- Kawakami, T., Sakaguchi, K., Takechi, K., Takano, H. and Takio, S. (2008) Ammonium induced expression of the red algal chloroplast gene Ycf18, a putative homolog of the cyanobacterial NblA gene involved in nitrogen deficiency-induced phycobilisome degradation. Biosci. Biotechnol. Biochem. 73, 740-743.
- Lin, X., Minamisawa, N., Takechi, K., Zhang, W., Sato, H., Takio, S., Tsukaya, H. Takano, H. (2008) Isolation and characterization of the Larix gmelinii ANGUSTIFOLIA (LgAN) gene. Planta 228, 601-608.
- Peddigari, S., Zhang, W., Sakai, M., Takechi, K., Takano, H. and Takio, S. (2008) A copia-like retrotansposon gene encoding gypsy-like integrase in a red alga, Porphyra yezoensis. J. Mol. Evol. 66, 72-79.
- Peddigari, S., Zhang, W., Takechi, K., Takano, H. and Takio, S. (2008) Two different clades of copia-like retrotransposons in the red alga, Porphyra yezoensis. Gene 424, 153-158.
- Saitoh, H. (2008) Sumoylation., Experimental Medicine 56, 1089 [in Japanese].
- Sekiyama, N., Ikegami, T., Yamane, T., Ikeguchi, M., Uchimura, Y., Baba, D., Ariyoshi, M., Tochio, H., Saitoh, H., Shirakawa, M. (2008) Structure of the SUMO-interacting motif of MBD1-containing chromatin-asociated factor 1(MCAF1) bound to SUMO-2., J. Biol. Chem. 283, 35966-35975.
- Schoenbach, K., Kolb, J., Xiao, S., Katsuki, S., Minamitani, Y., Joshi, R. (2008) Electrical breakdown of water in microgaps., Plasma Sources Science and Technology 17 (2), no. 024010
- Uwada, J., Saitoh, N., Nakao, M., Saitoh, H. (2008) Modulation of Nuclear Structure and Cancer Development by the SUMO Modification System., Science of Human Body 59, 352-353 [in Japanese].
- Yasuoka, K., Maehara, T., Katsuki, S., Namihira, T., Kaneko, T., Hatakeyama, R. (2008) Generation of underwater plasmas and their characteristics, J. Plasma and Fusion Research 84 (10), pp.666-673
- Zhang, C., Cheng, Y., Katsuki, S., Akiyama, H. (2008) Dependence of extreme ultraviolet emission on xenon flow rate from a Z-pinch discharge plasma., Japanese Journal of Applied Physics 47 (6), pp.4878-4880
- Heeren, T., Camp, J., Kolb, J., Schoenbach, K., Katsuki, S., Akiyama, H., (2007) 250 kV Sub-nanosecond Pulse Generator with Adjustable Pulse-width, IEEE Transactions on Dielectrics and Electrical Insulation 14 (4), pp. 884-888
- Ihara, M., Koyama, H., Uchimura, Y., Saitoh, H., Kikuchi, A. (2007) Noncovalent Binding of Small Ubiquitin-related Modifier (SUMO) Protease to SUMO is Necessary for Enzymatic Activities and Cell Growth. J. Biol. Chem. 282, 16465-16475.
- Katsuki, S., Nomura, N, Koga, H., Akiyama, H., Uchida, I., Abe, S-I. (2007) Biological effects of narrow band pulsed electric fields, IEEE Transactions on Dielectrics and Electrical Insulation 14 (3), pp. 663-668
- Namihira, T., Sakai, S., Yamaguchi, T., Yamamoto, K., Yamada, C., Kiyan, T., Sakugawa, T., Katsuki, S., Akiyama, H. (2007) Electron temperature and electron density of underwater pulsed discharge plasma produced by solid-state pulsed-power generator, IEEE Transactions on Plasma Science 35 (3), pp.614-618.
- Nozaki, H., Takano, H., Misumi, O., Terasawa, K., Matuzaki, M., Maruyama, S., Nishida, K., Yagisawa, F., Yoshida, Y., Fujiwara, T., Takio, T., Tamura, K., Chung, S. J., Nakamura, S., Kuroiwa, H., Tanaka, K., Sato, N. and Kuroiwa, T. (2007) A 100%-complete sequence reveals unusually simple genomic features in the hot spring red alga Cyanidioschyzon merolae. BMC Biology 5:28.
- Ono, Y., Sakai, A., Takechi, K., Takio, S., Takusagaea, M. and Takano, H. (2007) NtPolI-like1 and NtPolI-like2, bacterial DNA polymerase I homologues isolated from BY-2 cultured tobacco cells, encode DNA polymerases engaged in DNA replication in both plastids and mitochondria. Plant Cell Physiol. 48, 1679-1692.
- Zhang, C.H., Katsuki, S., Shi, J.G., Horita, H., Namihira, T., Akiyama, H. (2007) Characterization of solid tin target for gas discharges produced EUV plasmas, Solid State Phenomena 121-123 (PART 2), pp. 885-888
- Zhang, W., Lin, X., peddigari, S., Takechi,, K., Takano, H. and Takio, S. (2007) Characterization of short interspersed elements (SINEs) in a red alga, Porphyra yezoensis. Biosci. Biotech. Biochem. 71, 618-622.